FOR SOUTH AFRICAN RESIDENTS

Frequently asked questions

Everyday, we receive e-mails from people wanting to enjoy their lives without constraints. In this collection we give answers to the most relevant questions concerning healthy legs and Antistax^®.

If you have a question that you don't find answered in our list, you can contact our Antistax^® team of experts by the contact form on this website. We'll respond as quickly as possible. All e-mails will be treated as entirely confidential.

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Are there any known medicine interactions with Antistax^® tablets

There has been no specific medicine interaction studies conducted with Antistax^® tablets. If you are taking any other medicine, including complementary or traditional medicines, check with your healthcare professional before taking Antistax^® tablets.
I've been taking Antistax^® tablets for two weeks.When will they start to work?

Antistax^® tablets can be taken daily according to the product label. In clinical studies the beneficial therapeutic effect has been demonstrated within 2 weeks of use, with continued use for 6 weeks and up until 12 weeks³. There are currently no clinical data available for periods longer than 3 months of use.
Can I carry on taking Antistax^® tablets after six weeks?

Beneficial therapeutic effect has been demonstrated within 6 weeks of use. Studies show optimal benefit after 12 weeks of use³.
Does it matter what time of day I take Antistax^® tablets ?

Antistax^® tablets should be taken once daily and swallowed whole with water, in the morning before food.
I wear stockings with elastic support – can I take Antistax^® tablets?

Antistax^® tablets can be taken with support stockings².
Can Antistax^® tablets be taken alongside other vitamin and mineral supplements?

Consult your healthcare professional on how to best manage administration of concomitant medications when taking Antistax^®. Interactions with other medications such as vitamin and mineral supplements have not been studied.

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Listen to your Legs. Take Antistax^®.

ANTISTAX® Active Leg tablets. Reg. no.:48/32.2/1076. Each tablet contains dry extract of red vine leaf AS 195 (4 - 6:1) 360 mg per tablet. For full prescribing information refer to the professional information approved by the South African Health Products Regulatory Authority (SAHPRA).

ANTISTAX® Double Fresh Gel contains Red Vine Leaf Extract. Western herbal. This unregistered medicine has not been evaluated by the SAHPRA for its quality, safety or intended use.

HCR: Imperial Market Access Healthcare SA (Pty) Ltd, 10 Skeen Boulevard, Bedfordview, Gauteng, 2007. Reg. no.: 2006/029994/07.

General contact information: info.mahsa.sm@dpworld.com Tel: 012 621 4300. For any quality or safety related queries, please contact Imperial Quality at Quality.healthcare.sm@dpworld.com or Imperial Medical at pvimperiallogistics@dpworld.com.

References: 1. Antistax PIL 2. Antistax Double Fresh Gel PIL 3. Kiesewetter H. Koscielny J, Kalus U et al. Efficacy of orally administered extract of red vine leaf AS 195 (folia vitis viniferae) in chronic venous insufficiency (stages I-II): a randomised, double-blind, placebo-controlled trial. Arzneim.-Forsch./Drug Res 2000;50(1):109-117. 4. Kalus U, Koscielny J, Grigorov A et al. Improvement of cutaneous microcirculation and oxygen supply in patients with Chronic Venous Insufficiency by orally administered extract of red vine leaves AS 195: a randomised, double-blind, placebo-controlled, crossover study. Drugs R&D 2004; 5(2): 63-71. 5. Nees S, Weiss DR, Reichenblach-Klinke E et al. Protective Effects of Flavonoids Contained in the Red Vine Leaf on Venular Endothelium against the Attack of Activated Blood Components in vitro. Arzneim.-Forsch./Drug Res. 2003;53(5):330-341. 6. (last accessed 12 December 2023) 7. Francoise Pitsch. Results of the DECIDE survey: appraisal of the predictive value for chronic venous disease of a symptom. Phlebolymphology Vol 18. No. 3. 2011 8. NCBI - WWW Error Blocked Diagnostic (last accessed 13 December 2023) 9. The Epidemiology of Chronic Venous Insufficiency and Varicose Veins by Jennifer L. Beebe-Dimmer, John R Pfeifer, Jennifer S. Engle and David Schottenfeld. March 2005 SAZA.ANTI.19.08.0315

Frequently asked questions

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